Cardiac & Neuro Protection Laboratories

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Full Time Faculty, Staff, Postdoctoral Fellows & Graduate Students

Hemal PatelHemal Patel, PhD

DawnaDawna Chuss

Patel_piyushPiyush Patel, MD

Dr-Head-PixBrian Head, PhD

rothDavid Roth, MD, PhD

AliceZemljic-Harpf, Alice, MD

Matt PMatthew Pearn, MD Matt SMatt Spellman

ShanshanShanshan Wang, MD,
PhD

Juan_11192018
Juan Zuniga Hertz, PhD

Zhou_photo

Kimberly Zhou, MD

MyPhoto_1176229658_0498

Young Sun, MD

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Mckenzie Pavlich

Antoinette

Antoinette Ronquillo


Melody Nazarbegian
Thio.jpg
Marianne Thio

Undergraduate Students

Isabella
Isabella Kelly

paul
Paul Savchenko

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RSS hemal h patel

  • Loss of cAMP signaling in CD11c immune cells protects against diet-induced obesity
  • BJP recommendations for publishing research on tobacco smoke and environmental tobacco smoke exposure
  • Considering and reporting sex as an experimental variable II: An update on progress in the British Journal of Pharmacology
  • Impact of blood factors on endothelial cell metabolism and function in two diverse heart failure models
  • Very Low Driving-Pressure Ventilation in Patients With COVID-19 Acute Respiratory Distress Syndrome on Extracorporeal Membrane Oxygenation: A Physiologic Study
  • Guidance for the use and reporting of anaesthetic agents in BJP manuscripts involving work with animals
  • Age-Dependent Behavioral and Metabolic Assessment of App NL-G-F/NL-G-F Knock-in (KI) Mice
  • Subpial delivery of adeno-associated virus 9-synapsin-caveolin-1 (AAV9-SynCav1) preserves motor neuron and neuromuscular junction morphology, motor function, delays disease onset, and extends survival in hSOD1G93A mice
  • Planning experiments: Updated guidance on experimental design and analysis and their reporting III
  • Caveolin-1 controls mitochondrial damage and ROS production by regulating fission - fusion dynamics and mitophagy

RSS david m roth, patel

  • Impact of blood factors on endothelial cell metabolism and function in two diverse heart failure models
  • Subpial delivery of adeno-associated virus 9-synapsin-caveolin-1 (AAV9-SynCav1) preserves motor neuron and neuromuscular junction morphology, motor function, delays disease onset, and extends survival in hSOD1G93A mice
  • Extracellular Vesicles: A New Paradigm for Cellular Communication in Perioperative Medicine, Critical Care, and Pain Management
  • Synapsin-caveolin-1 gene therapy preserves neuronal and synaptic morphology and prevents neurodegeneration in a mouse model of AD
  • Immunosuppression of Macrophages Underlies the Cardioprotective Effects of CST (Catestatin)
  • Morphine induces physiological, structural, and molecular benefits in the diabetic myocardium
  • Protective role of cardiac-specific overexpression of caveolin-3 in cirrhotic cardiomyopathy
  • Dexmedetomidine and Cardiac "Postconditioning": Clearing the Dex for Clinical Application
  • 1 + 1 = 4? Balanced anaesthesia: A sum that is greater than its parts
  • Caveolin-1 Phosphorylation Is Essential for Axonal Growth of Human Neurons Derived From iPSCs

RSS brian p head

  • Age-Dependent Behavioral and Metabolic Assessment of App NL-G-F/NL-G-F Knock-in (KI) Mice
  • Subpial delivery of adeno-associated virus 9-synapsin-caveolin-1 (AAV9-SynCav1) preserves motor neuron and neuromuscular junction morphology, motor function, delays disease onset, and extends survival in hSOD1G93A mice
  • Amyloidogenic Processing of Amyloid Precursor Protein Drives Stretch-Induced Disruption of Axonal Transport in hiPSC-Derived Neurons
  • Synapsin-Promoted Caveolin-1 Overexpression Maintains Mitochondrial Morphology and Function in PSAPP Alzheimer's Disease Mice
  • Caveolin-1 Expression in the Dorsal Striatum Drives Methamphetamine Addiction-Like Behavior
  • Synapsin-caveolin-1 gene therapy preserves neuronal and synaptic morphology and prevents neurodegeneration in a mouse model of AD
  • Preclinical validation of a potent γ-secretase modulator for Alzheimer's disease prevention
  • Morphine induces physiological, structural, and molecular benefits in the diabetic myocardium
  • Abstinence from ethanol dependence produces concomitant cortical gray matter abnormalities, microstructural deficits and cognitive dysfunction
  • Ultrashort echo time (UTE) magnetic resonance imaging of myelin: technical developments and challenges

RSS piyush m patel

  • Fixed-Dose Combination of Dapagliflozin + Sitagliptin + Metformin in Patients with Type 2 Diabetes Poorly Controlled with Metformin: Phase 3, Randomized Comparison with Dual Combinations
  • Subpial delivery of adeno-associated virus 9-synapsin-caveolin-1 (AAV9-SynCav1) preserves motor neuron and neuromuscular junction morphology, motor function, delays disease onset, and extends survival in hSOD1G93A mice
  • Synapsin-caveolin-1 gene therapy preserves neuronal and synaptic morphology and prevents neurodegeneration in a mouse model of AD
  • Morphine induces physiological, structural, and molecular benefits in the diabetic myocardium
  • Caveolin-1 Phosphorylation Is Essential for Axonal Growth of Human Neurons Derived From iPSCs
  • Neuron-targeted caveolin-1 improves neuromuscular function and extends survival in SOD1G93A mice
  • Relations of combat stress and posttraumatic stress disorder to 24-h plasma and cerebrospinal fluid interleukin-6 levels and circadian rhythmicity
  • Neuron-Targeted Caveolin-1 Promotes Ultrastructural and Functional Hippocampal Synaptic Plasticity
  • Neuron-specific caveolin-1 overexpression improves motor function and preserves memory in mice subjected to brain trauma
  • Caveolin-1 regulation of disrupted-in-schizophrenia-1 as a potential therapeutic target for schizophrenia

RSS Latest Publications on Caveolin

  • Polarized Mechanosensitive Signaling Domains Protect Arterial Endothelial Cells Against Inflammation
  • Monochasma savatieri Inhibits the Migration of the Breast Cancer Cell Line MDA- MB-231
  • Autophagy-Interfering Nanoboat Drifting along CD44-Golgi-ER Flow as RNAi Therapeutics for Hepatic Fibrosis
  • Insulin Resistance Triggers Atherosclerosis: Caveolin 1 Cooperates with PKCzeta to Block Insulin Signaling in Vascular Endothelial Cells
  • The Role of Membrane Lipids in the Formation and Function of Caveolae
  • Interleukin-37 inhibits desmoglein-3 endocytosis and keratinocyte dissociation via upregulation of Caveolin-1 and inhibition of the STAT3 pathway
  • The redox activity of polychlorinated biphenyl quinone metabolite orchestrates its pro-atherosclerosis effect via CAV1 phosphorylation
  • Vitamin D receptor (VDR) on the cell membrane of mouse macrophages participates in the formation of lipopolysaccharide tolerance: mVDR is related to the effect of artesunate to reverse LPS tolerance
  • Caveolin-1 and Atherosclerosis: Regulation of LDLs Fate in Endothelial Cells
  • Lipid Emulsion Inhibits Amlodipine-Induced Nitric Oxide-Mediated Vasodilation in Isolated Rat Aorta
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